Dynamic Optimization in Radiotherapy

The generation of intensity-modulated fields for conformal radiotherapy by dynamic collimation

An algorithm has been developed to calculate the collimator jaw motions required to generate intensity-modulated fields far use in conformal radiotherapy. The dynamic technique allows arbitrary intensity profiles to he generated using a single unidirectional sweep of the collimators. The collimator jaws have independent motion, so that an aperture of variable width is scanned across the field. ...

Optimization of Beam Orientation and Weight in Radiotherapy Treatment Planning using a Genetic Algorithm

Introduction: The selection of suitable beam angles and weights in external-beam radiotherapy is at present generally based upon the experience of the planner. Therefore, automated selection of beam angles and weights in forward-planned radiotherapy will be beneficial. Material and Methods: In this work, an efficient method is presented within the MATLAB environment to investigate how to improv...

Stochastic programming for off-line adaptive radiotherapy

In intensity-modulated radiotherapy (IMRT), a treatment is designed to deliver high radiation doses to tumors, while avoiding the healthy tissue. Optimizationbased treatment planning often produces sharp dose gradients between tumors and healthy tissue. Random shifts during treatment can cause significant differences between the dose in the “optimized” plan and the actual dose delivered to a pa...

Clustering and Memory-based Parent-Child Swarm Meta-heuristic Algorithm for Dynamic Optimization

So far, various optimization methods have been proposed, and swarm intelligence algorithms have gathered a lot of attention by academia. However, most of the recent optimization problems in the real world have a dynamic nature. Thus, an optimization algorithm is required to solve the problems in dynamic environments well. In this paper, a novel collective optimization algorithm, namely the Clus...

Optimization of Breast Cancer Treatment by Dynamic Intensity Modulated Electron Radiotherapy

Optimization of Radiation Dose in Cranial Computed Tomography among Adults: Assessment of Radiation Dose against Image Quality

Introduction: The rapid use of computed tomography (CT) scan is of great concern, due to increase in patients’ dose. Optimization of CT protocol is a vital issue in dose reduction. This study aimed to optimize radiation dose in cranial CT and assess modifications in image quality under radiation dose reduction. Material and Methods: A poly(me...